Danny Soares MD

Pathophysiology of ischaemia

Saturday 19th November, 11:10


The popularity of injectable HA fillers has brought an increase in the incidence of once-rare iatrogenic vaso-occlusive injuries ranging from disfiguring facial skin necrosis to disabling neuro-ophthalmological sequelae. As our understanding of the pathophysiology of these injuries has evolved, the formulation of novel therapeutic and preventative strategies has permitted the amelioration of this burdensome complication. In this presentation, we review the relevant mechanisms underlying HA filler-induced vascular occlusion (FIVO), with particular emphasis on the rheo-mechanical aspects of vascular blockade, the thromboembolic potential of HA mixtures, and the tissue-specific ischemic susceptibility of microvascular networks leading to injury.

Dr. Soares is a double-board certified facial plastic & reconstructive surgeon and assistant professor at the University of Central Florida, College of Medicine. He is the co-founder and president of the American Foundation for Aesthetic Medicine (AFFAM), a non-profit organization dedicated to the fellowship-training of non-physician practitioners in aesthetics. His active areas of interest & research include the ligamentous and vascular anatomy of the face and the pathophysiology of filler-induced vascular occlusion. He is the host and content creator for the YouTube channel Aesthetic Minutes, which provides educational content in facial plastic surgery for the general public. Dr. Soares serves as the medical director of the Village institute of Plastic Surgery, and as program director for the facility’s aesthetic medicine fellowship.